Warhammer 40,000: Conquest is a two-player Living Card Game® of interplanetary warfare in the gritty futuristic setting of Warhammer 40,000. By hurling you into a life-and-death combat for the Traxis sector, Warhammer 40,000: Conquest forces you to secure your hold over the sector’s key planets. You must balance the concerns of present battles and future conquests as your warlord leads your armies to glorious victory. To claim the Traxis sector, you must conquer or die.

In the game, each player controls one warlord and his armies as you engage in interplanetary warfare. Warhammer 40,000: Conquest introduces seven distinct factions: Space Marines, Imperial Guard, Orks, Chaos, Dark Eldar, Eldar, and Tau. Each of these factions possesses a unique flavor and style of play, and an alignment wheel introduces the possibility of forming an alliance between two factions.